YOUNG SMALL EXTRACELLULAR VESICLES REJUVENATE REPLICATIVE SENESCENCE BY REMODELING DRP1 TRANSLOCATION-MEDIATED MITOCHONDRIAL DYNAMICS

Young small extracellular vesicles rejuvenate replicative senescence by remodeling Drp1 translocation-mediated mitochondrial dynamics

Abstract Background Human mesenchymal stem cells have attracted interest in regenerative medicine and are being tested in many clinical trials.In vitro expansion is necessary to provide clinical-grade quantities of mesenchymal stem cells; however, it has Funko Pop! been reported to cause replicative senescence and undefined dysfunction in mesenchym

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The role and value of science in shark conservation advocacy

Abstract Many species of sharks are threatened with extinction, and there has been a longstanding debate in scientific and environmental circles over the most effective and appropriate strategy to conserve and protect them.Should we allow for sustainable fisheries exploitation of species which can withstand fishing pressure, or ban all fisheries fo

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Strategies for Interfering With Bacterial Early Stage Biofilms

Biofilm-related bacteria show high resistance to antimicrobial treatments, posing a remarkable challenge to human health.Given bacterial dormancy dry shampoo and high expression of efflux pumps, persistent infections caused by mature biofilms are not easy to treat, thereby driving researchers toward the discovery of many anti-biofilm molecules that

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Lotus (Nelumbo nucifera): a multidisciplinary review of its cultural, ecological, and nutraceutical significance

Abstract This comprehensive review systematically examines the multifarious aspects of Nelumbo nucifera, elucidating its ecological, nutritional, medicinal, and biomimetic significance.Renowned both culturally and scientifically, Nelumbo nucifera manifests remarkable adaptability, characterized by its extensive distribution across varied climatic r

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